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Updated: Apr 18, 2026

Ovarian Tissue Culture to Visualize Phenomena in Mouse Ovary
Published on: June 19, 2018
The bone morphogenetic protein system and the regulation of ovarian follicle development in mammals
Rodrigo O D S Rossi1, José J N Costa1, Anderson W B Silva1
1Biotechnology Nucleus of Sobral - NUBIS,Federal University of Ceara,Sobral,CE,Brazil.
Abstract:
The bone morphogenetic protein (BMP) family consists of several growth factor proteins that belong to the transforming growth factor-β (TGF-β) superfamily. BMPs bind to type I and type II serine-threonine kinase receptors, and transduce signals through the Smad signalling pathway. BMPs have been identified in mammalian ovaries, and functional studies have shown that they are involved in the regulation of oogenesis and folliculogenesis. This review summarizes the role of the BMP system during formation, growth and maturation of ovarian follicles in mammals.
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