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The effect of shift work on red blood cell distribution width
1The University of Mississippi, Center for Health Behavior Research, University, MS, United States.
Physiology & Behavior
|January 24, 2015
Summary
Rotating shift work is linked to higher red blood cell distribution width (RDW) in women. Elevated RDW is a risk factor for cardiovascular disease, highlighting potential occupational health concerns.
Area of Science:
- Occupational Health
- Cardiovascular Disease Biomarkers
- Hematology
Background:
- Shift work is associated with adverse health outcomes like metabolic syndrome.
- Red blood cell distribution width (RDW) is an emerging biomarker for cardiovascular disease risk.
Purpose of the Study:
- To investigate the association between shift work and RDW.
- To determine if shift work impacts this novel cardiovascular disease biomarker.
Main Methods:
- Utilized data from the 2005-2010 National Health and Nutrition Examination Survey (NHANES).
- Assessed RDW from blood samples and shift work via questionnaire.
- Controlled for demographic, behavioral, psychological, occupational, and biological factors.
Main Results:
- Women working rotating shifts had a 46% increased odds of elevated RDW compared to day shift workers (OR=1.46; 95% CI: 1.03-2.08).
- This association remained significant after full adjustment for covariates.
Conclusions:
- Rotating shift work may increase the risk of elevated RDW in women.
- Elevated RDW is a known risk factor for cardiovascular disease and mortality.
- Clinicians should inquire about work schedules and tolerance to identify at-risk individuals.
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