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[Ankyloblepharon filiforme adnatum and associated syndromes]
J Bursztyn1, C Guillem, D Ginisty
1Service d'Ophtalmologie, Hôpital de la Pitié, Paris.
Journal Francais D'Ophtalmologie
|January 1, 1989
Summary
Ankyloblepharon filiforme adnatum (AFA) is an ocular anomaly. This review discusses two cases, one isolated and one associated with popliteal pterygium syndrome, examining AFA
Area of Science:
- Ophthalmology
- Medical Genetics
Background:
- Ankyloblepharon filiforme adnatum (AFA) is a rare congenital ocular anomaly characterized by the adherence of the eyelid margins.
- Understanding its etiology and associated conditions is crucial for comprehensive patient management.
Observation:
- Two distinct cases of AFA are presented.
- Case 1: Isolated AFA without other systemic malformations.
- Case 2: AFA associated with popliteal pterygium syndrome, highlighting syndromic AFA.
Findings:
- The review covers histologic and embryologic features of AFA.
- Etiopathogenic theories and associated syndromes are discussed, including Rosenman's classification.
- The spectrum of AFA presentation ranges from isolated findings to complex syndromes.
Implications:
- Accurate diagnosis and classification of AFA are essential for identifying associated syndromes.
- This review provides a comprehensive resource for clinicians managing AFA and related conditions.
- Further research into the genetic and developmental pathways of AFA may improve understanding and treatment.