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Clinics of ocular tuberculosis
Vishali Gupta1, Samir S Shoughy, Sarakshi Mahajan
1Postgraduate Institute of Medical Education and Research Chandigarh , Advanced Eye Centre , India .
Ocular Immunology and Inflammation
|January 24, 2015
Summary
Ocular tuberculosis presents with diverse symptoms affecting various eye parts. Early recognition of these clinical signs is crucial for timely diagnosis and treatment of this extrapulmonary condition.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Ocular tuberculosis is an extrapulmonary manifestation of Mycobacterium tuberculosis infection.
- It presents with a wide spectrum of clinical signs affecting both anterior and posterior segments of the eye.
- Manifestations can occur in both immunocompetent and immunocompromised individuals.
Purpose of the Study:
- To review and describe the clinical manifestations of ocular tuberculosis.
- To cover presentations in both anterior and posterior segments of the eye.
- To include findings in immunocompetent and immunocompromised patients.
Main Methods:
- Literature review.
- Search of the Pubmed database for relevant studies.
Main Results:
- Anterior segment involvement includes conjunctival granuloma, nodular scleritis, interstitial keratitis, lacrimal gland/orbital granulomas, anterior granulomatous uveitis, synechiae, secondary glaucoma, and cataract.
- Posterior segment manifestations comprise vitritis, retinal vasculitis, optic neuritis, choroiditis, choroidal tubercles, subretinal neovascularization, and endophthalmitis.
- Mycobacterium tuberculosis can affect intraocular structures, including the ciliary body, leading to caseating granulomas.
Conclusions:
- Recognizing the clinical signs of ocular tuberculosis is essential for diagnosis.
- Early identification facilitates targeted investigations.
- Prompt initiation of anti-tuberculosis therapy is guided by clinical presentation.
Keywords:
Anterior granulomatous uveitisintermediate uveitisocular tuberculosis, posterior uveitisscleritisMore Related Videos
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