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[Peripheral neuropathy in HIV infection].

A Cruz Martínez, M Lara, C Villoslada

    Archivos De Neurobiologia
    |January 1, 1989
    PubMed
    Summary

    Human immunodeficiency virus (HIV) infection can cause various neuropathies. Early screening for HIV is crucial in patients with unexplained motor demyelinating neuropathies.

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    Area of Science:

    • Neurology
    • Infectious Diseases
    • Pathology

    Context:

    • Neuropathy is a common complication across all stages of human immunodeficiency virus (HIV) infection.
    • Various peripheral neuropathies and myelopathies are associated with HIV, including sensory polyneuropathy, demyelinating polyneuropathies, mononeuropathy multiplex, and sensory ataxic neuropathy.
    • Subclinical neuropathy can be detected via electrophysiologic studies.

    Purpose:

    • To describe the clinical, electrophysiological, and pathological features of HIV-associated neuropathies.
    • To discuss the pathogenesis and treatment strategies for these neurological complications.
    • To report findings from a series of twenty-two patients with HIV-related neuropathy.

    Summary:

    • The study details diverse HIV-associated neuropathies, emphasizing their clinical presentation, electrodiagnostic findings, and pathology.
    • Three cases highlight chronic demyelinating polyneuropathy as an initial manifestation of HIV infection.
    • Recommendations include screening patients with motor demyelinating neuropathies and risk factors for silent HIV.

    Impact:

    • Highlights the importance of recognizing neuropathy as an early sign of HIV infection.
    • Suggests a diagnostic approach for identifying undiagnosed HIV in patients presenting with specific neurological symptoms.
    • Contributes to understanding the spectrum and management of neurological disorders in the context of HIV.

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