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Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia in pregnancy

Candace B Mainor1, Alison P Duffy2, Kristin L Atkins3

  • 1Department of Medicine, University of Maryland School of Medicine, Baltimore, USA cmainor@umm.edu.

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners
|January 25, 2015
PubMed

BCR-ABL inhibitors administered in conjunction with chemotherapy have significantly improved outcomes in Philadelphia chromosome-positive acute lymphoblastic leukemia but, for patients diagnosed during pregnancy, data on risks to the fetus are limited. We report a woman treated with chemotherapy and imatinib mesylate who delivered a healthy baby at 30 weeks, and we discuss available data.

Keywords:
Acute lymphoblastic leukemiaimatinib mesylatepregnancy

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