Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nonstrangulating intestinal infarctions associated with Strongylus vulgaris: Clinical presentation and treatment outcomes of 30 horses (2008-2016).

Equine veterinary journal·2017
Same author

Serotonin markers show altered transcription levels in an experimental pig model of mitral regurgitation.

Veterinary journal (London, England : 1997)·2015
Same author

Distribution and histopathological changes induced by cysts of Taenia solium in the brain of pigs from Tanzania.

Journal of helminthology·2014
Same author

Distribution and histopathological changes induced by cysts of Taenia solium in the brain of pigs from Tanzania.

Journal of helminthology·2014
Same author

Strong association between activated valvular interstitial cells and histopathological lesions in porcine model of induced mitral regurgitation.

International journal of cardiology·2014
Same author

Porcine melanotic cutaneous lesions and lymph nodes: immunohistochemical differentiation of melanocytes and melanophages.

Veterinary pathology·2014

Related Experiment Video

Updated: Apr 18, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

5.0K

Segmental Arterial Mediolysis in Pigs Presenting With Renal Infarcts.

P S Leifsson1, R E Slavin2

  • 1Department of Veterinary Disease Biology, University of Copenhagen, Copenhagen, Denmark ple@sund.ku.dk.

Veterinary Pathology
|January 25, 2015
PubMed
Summary

Segmental arterial mediolysis, a rare kidney arteriopathy, was identified in pigs. This condition involves lesions in interlobar and arcuate arteries, leading to potential renal infarcts and unknown causes.

Keywords:
arterydissecting hematomaspigsrenal infarctssegmental arterial mediolysisvasculopathy

More Related Videos

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

9.3K
Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock
07:48

Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock

Published on: October 28, 2022

1.7K

Related Experiment Videos

Last Updated: Apr 18, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

5.0K
Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

9.3K
Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock
07:48

Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock

Published on: October 28, 2022

1.7K

Area of Science:

  • Veterinary Pathology
  • Arterial Diseases
  • Renal Pathophysiology

Background:

  • Segmental arterial mediolysis (SAM) is a rare arteriopathy primarily documented in humans.
  • Kidney lesions in pigs, including hemorrhagic or pale cortical areas, suggest an underlying vascular pathology.

Purpose of the Study:

  • To describe the pathological findings of segmental arterial mediolysis in the kidneys of pigs.
  • To investigate the arterial lesions and their sequelae in affected porcine kidneys.

Main Methods:

  • Macroscopic examination of pig kidneys from an abattoir.
  • Histopathological analysis of interlobar and arcuate arteries to identify injurious and reparative phases of vascular lesions.

Main Results:

  • Segmental arterial mediolysis was observed in 36 pigs, affecting interlobar and arcuate arteries.
  • Injurious lesions included separation of the media from adventitia and vacuolar changes in smooth muscle cells.
  • Reparative phases involved granulation tissue, leading to arterial occlusion, dissecting hematomas, and renal infarcts.

Conclusions:

  • The study describes SAM in a porcine population, highlighting its pathological features and potential sequelae.
  • The exact causation of SAM in these pigs remains undetermined, with no identified link to repartitioning agents.