Related Experiment Video
Updated: Feb 7, 2026

07:34
Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
Published on: December 15, 2023
3.4K
Imaging selection for reperfusion therapy in acute ischemic stroke.
Jeremy J Heit1, Max Wintermark
1Department of Radiology, Neuroradiology Division, Stanford University, 300 Pasteur Drive, Room S047, Stanford, CA, 94305, USA.
Current Treatment Options in Neurology
|January 27, 2015
Summary
Neuroimaging, including CT and MRI, is crucial for diagnosing acute stroke and guiding treatment. Advanced techniques like CT-angiography and perfusion imaging help identify eligible patients for reperfusion therapies.
Area of Science:
- Neurology
- Radiology
- Emergency Medicine
Background:
- Neuroimaging plays a critical role in the immediate assessment of patients presenting with suspected acute stroke.
- Accurate diagnosis is essential to differentiate true strokes from stroke mimics and to determine appropriate treatment pathways.
Purpose of the Study:
- To outline the essential role of neuroimaging in the acute stroke workflow.
- To detail the utility of various neuroimaging modalities in guiding reperfusion therapies.
Main Methods:
- Review of current neuroimaging techniques used in acute stroke evaluation.
- Discussion of criteria for selecting patients for intravenous thrombolysis and endovascular therapy.
Main Results:
- Computed tomography (CT) and magnetic resonance imaging (MRI) are fundamental for diagnosis and triage.
- Advanced imaging like CT-angiography, MR-angiography, CT-perfusion, and MR-perfusion provide critical data for treatment decisions.
- Key criteria for endovascular therapy include accessible occlusion, small infarct core, and significant penumbra.
Conclusions:
- Neuroimaging is indispensable for the timely and effective management of acute stroke.
- Advanced neuroimaging techniques optimize patient selection for reperfusion therapies, improving outcomes.
More Related Videos
Related Concept Videos
Types of Selection
45.2K
Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
45.2K
Regulation of Stroke Volume
5.2K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
5.2K
Gene Therapy
27.6K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.6K
What is Natural Selection?
129.6K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
129.6K
Antibiotic Selection
60.0K
Overview
60.0K
Group Therapy
450
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
450

