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A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
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Marine natural products.

John W Blunt1, Brent R Copp, Robert A Keyzers

  • 1Department of Chemistry, University of Canterbury, Christchurch, New Zealand. john.blunt@canterbury.ac.nz.

Natural Product Reports
|January 27, 2015
PubMed
Summary

This review summarizes 2013 literature on marine natural products (MNPs). It details new compounds from diverse marine organisms and their biological activities, aiding drug discovery research.

Area of Science:

  • Marine Biology
  • Natural Products Chemistry
  • Pharmacology

Background:

  • Marine natural products (MNPs) are a rich source of novel chemical entities.
  • Research in MNP discovery has expanded significantly, with numerous publications annually.
  • Understanding the origins and activities of MNPs is crucial for drug development.

Purpose of the Study:

  • To provide a comprehensive overview of MNPs reported in the literature from 2013.
  • To highlight newly discovered compounds, their biological activities, and sources.
  • To consolidate information on biosynthetic studies, syntheses, and structural revisions of MNPs.

Main Methods:

  • Systematic literature search for marine natural products published in 2013.
  • Categorization of compounds based on source organisms (e.g., algae, sponges, microorganisms).

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  • Inclusion of data on biological activities, country of origin, and synthetic studies.

    • Main Results:

    • The review covers 982 citations related to MNPs, with 644 specific to 2013.
    • 1163 new compounds were identified and described.
    • Data on biological activities, source organisms, and geographical origin were compiled.

    Conclusions:

    • The year 2013 was highly productive in the field of marine natural products research.
    • Continued exploration of marine biodiversity yields novel compounds with potential therapeutic applications.
    • This review serves as a valuable resource for researchers in natural product chemistry and drug discovery.