Abnormal liver function induced by myofibroblastic sarcoma infiltrating the liver: A case report

Area of Science:

• Oncology
• Pathology
• Gastroenterology

Background:

• Myofibroblastic sarcoma (MS) is a rare malignancy typically affecting the head, neck, and extremities.
• While MS in other head and neck sites has been documented, hepatic MS remains unreported.
• Liver dysfunction can arise from various hepatic pathologies, necessitating thorough investigation of rare tumors.

Purpose of the Study:

• To present the first reported case of myofibroblastic sarcoma (MS) of the liver.
• To discuss the clinical, biochemical, imaging, and pathological features of hepatic MS.
• To enhance the understanding and knowledge base of this rare liver malignancy.

Main Methods:

• Case report of a 38-year-old female patient.
• Review of clinical, biochemical, imaging, and pathological data.
• Discussion of the patient's presentation, treatment, and follow-up.

Main Results:

• A 38-year-old female presented with a retroperitoneal mass, later diagnosed as hepatic myofibroblastic sarcoma (MS).
• The diagnosis was made three months post-initial surgical treatment.
• The patient refused further treatment and was lost to follow-up.

Conclusions:

• This case represents the first documented instance of myofibroblastic sarcoma (MS) originating in the liver.
• Hepatic MS can lead to impaired liver function.
• Further research and case reporting are crucial for understanding this rare condition.