Early and late operation of cleft lip and intelligence quotient and psychosocial development in 3-7 years

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Irena Petráčková1, Jiří Zach1, Jiří Borský2

  • 1Department of Pediatrics/Neonatology, Thomayer Hospital Prague, Videnska 800, Praha 4 14059, Czech Republic.

Early Human Development
|January 27, 2015
PubMed

Insights

Early cleft lip repair in infants did not negatively impact intelligence quotient (IQ) and showed improved psychosocial development. This study compared outcomes for early versus late surgical repair in children operated on within their first year of life.

Area of Science:

  • Pediatric Surgery
  • Developmental Psychology
  • Anesthesiology

Background:

  • Cleft lip repair involves general anesthesia in the first year of life, raising concerns about long-term neurological effects.
  • The timing of cleft lip surgery may influence a child's quality of life and family acceptance.

Purpose of the Study:

  • To compare outcomes between infants undergoing early versus late cleft lip repair within the first year of life.
  • To assess the impact of surgical timing on neurological and psychosocial development.

Main Methods:

  • Observational cohort study comparing two groups: early repair (first 8 days) and late repair (3-10 months).
  • Intelligence quotient (IQ) and psychosocial development were evaluated in children aged 3-7 years.

Main Results:

  • No significant differences in IQ were observed between the early and late repair groups (IQ within normal range for both).
  • Children in the early repair group demonstrated significantly better physical functioning (P=0.042) and self-esteem (P=0.014).

Conclusions:

  • Early cleft lip repair does not negatively affect intelligence quotient by age 3-7 years.
  • Earlier surgical intervention for cleft lip is associated with positive impacts on specific aspects of psychosocial development.
Abstract

Keywords:
AnesthesiaCleft lipIntelligence quotientPsychosocial development

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