Related Experiment Video
Updated: Apr 18, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Use of a ventricular septal defect occluder for apical closure in transapical aortic valve replacement
Enrico Ferrari1, Didier Locca, Denis Berdajs
1From the *Cardiac Surgery Unit, †Cardiology Unit, and ‡Cardiac Anesthesia Unit, University of Lausanne, Lausanne, Switzerland.
Abstract:
During transapical transcatheter aortic valve replacement (TA-TAVR), the apical closure remains a challenge for the surgeon, having the risk for ventricular tear and massive bleeding. Apical closure devices are already under clinical evaluation, but only a few can lead to a full percutaneous TA-TAVR. We describe the successful use of a 9-mm myocardial occluder (ventricular septal defect occluder) that was used to seal the apex after a standard TA-TAVR (using the Sapien XT 23-mm transcatheter valve and the Ascendra + delivery system). The placement of the nonmodified myocardial occluder was performed through the Ascendra + delivery system, with a very small amount of blood loss and an acceptable sealing of the apical tear. This approach is feasible and represents a further step toward true-percutaneous transapical heart valve procedures. Modified apical occluders are under evaluation in animal models.
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