Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

1.3K
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
1.3K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Superficial spreading (and disappearing) seborrheic keratosis.

Cutis·1999
Same author

Contact sensitivities in palmar plantar pustulosis (acropustulosis).

Contact dermatitis·1998
Same author

Weber-Christian panniculitis: a review of 30 cases with this diagnosis.

Journal of the American Academy of Dermatology·1998
Same author

Asteroid bodies and other cytoplasmic inclusions in necrobiotic xanthogranuloma with paraproteinemia.

Journal of the American Academy of Dermatology·1998
Same author

Intravenous immunoglobulin in autoimmune chronic urticaria.

The British journal of dermatology·1998
Same author

Giant cell granulomatous pulmonary and myocardial lesions in necrobiotic xanthogranuloma with paraproteinemia.

Mayo Clinic proceedings·1997

Related Experiment Video

Updated: Apr 18, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.7K

Autotransplantation in pustular psoriasis.

R W Fardal1, R K Winkelmann

  • 1Mayo Clinic, Rochester, Minnesota, USA.

The Journal of Investigative Dermatology
|January 28, 2015
PubMed
Summary

Transplanting skin showed that the soles of the feet can induce pustular psoriasis in normal skin. Conversely, affected skin became normal when moved to a different body location.

Area of Science:

  • Dermatology
  • Transplantation Biology

Background:

  • Pustular psoriasis of the soles is a chronic condition affecting plantar skin.
  • The etiology and localization of pustular psoriasis remain incompletely understood.

Purpose of the Study:

  • To investigate the role of local skin environment in the pathogenesis of pustular psoriasis of the soles.
  • To determine if plantar skin possesses inherent properties that induce or suppress psoriasis development.

Main Methods:

  • Full-thickness skin cylinders were transplanted between normal glabrous skin and involved plantar skin in five female patients with chronic pustular psoriasis of the soles.
  • One patient had concomitant psoriasis elsewhere on the body.

Main Results:

  • Normal glabrous skin transplanted to the plantar area developed typical pustular psoriasis.

More Related Videos

Murine Full-thickness Skin Transplantation
07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

21.8K
Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
11:47

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

Published on: February 21, 2016

12.8K

Related Experiment Videos

Last Updated: Apr 18, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.7K
Murine Full-thickness Skin Transplantation
07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

21.8K
Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
11:47

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

Published on: February 21, 2016

12.8K
  • Plantar skin previously affected by psoriasis reverted to normal scar tissue when transplanted to glabrous areas.

    • Conclusions:

    • The plantar skin environment appears to induce pustular psoriasis.
    • The local skin environment plays a critical role in the manifestation and localization of pustular psoriasis.