Related Experiment Video
Updated: Apr 18, 2026
The Miniature Pig: A Large Animal Model for Cochlear Implant Research
Published on: July 28, 2022
[Development of electrically evoked auditory brainstem response modules of REZ-I domestic cochlear implant device]
Xiuyong Ding1, Ruxiang Zhang, Changjian Xu
1Department of Otorhinolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Objective:
To develop electrically evoked auditory brainstem response(EABR) modules of REZ-I domestic cochlear implant device, and testify the reliability and validity of the modules.
Methods:
Postoperative EABR were recorded in guinea pigs by using the self-designed EABR module.
Results:
EABR waves were recorded in all 15 ears of 9 guinea pigs with normal hearing. The threshold was (159.00 ± 50.21) current level (CL) and eIII wave latency was (2.36 ± 0.46) ms of 100 µs pulse width stimulation; for 150 µs pulse width stimulation, the threshold was (131.44 ± 49.25) CL and eIII wave latency was (2.59 ± 0.46)ms; for 200 µs pulse width stimulation, the threshold was (119.63 ± 52.56) CL and e III wave latency was (2.62 ± 0.44)ms.
Conclusion:
According the preliminary results of the study, the reliability and stability of the EABR modules of domestic cochlear implant device can meet the demands of EABR recording.
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