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Updated: Apr 18, 2026

Study of Experimental Organ Donation Models for Lung Transplantation
Published on: March 15, 2024
Using an Extended Theory of Planned Behavior to Predict a Change in the Type of Blood Product Donated
Kathleen L Bagot1, Barbara M Masser, Katherine M White
1Public Health, The Florey Institute of Neurosciences and Mental Health, 245 Burgundy Street, Heidelberg, VIC, 3084, Australia, kathleen.bagot@florey.edu.au.
Background:
Demand for essential plasma-derived products is increasing.
Purpose:
This prospective study aims to identify predictors of voluntary non-remunerated whole blood (WB) donors becoming plasmapheresis donors.
Methods:
Surveys were sent to WB donors who had recently (recent n = 1,957) and not recently donated (distant n = 1,012). Theory of Planned Behavior (TPB) constructs (attitude, subjective norm, self-efficacy) were extended with moral norm, anticipatory regret, and donor identity. Intentions and objective plasmapheresis donation for 527 recent and 166 distant participants were assessed.
Results:
Multi-group analysis revealed that the model was a good fit. Moral norm and self-efficacy were positively associated while role identity (suppressed by moral norm) was negatively associated with plasmapheresis intentions.
Conclusions:
The extended TPB was useful in identifying factors that facilitate conversion from WB to plasmapheresis donation. A superordinate donor identity may be synonymous with WB donation and, for donors with a strong moral norm for plasmapheresis, may inhibit conversion.
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