Related Experiment Video
Updated: Apr 18, 2026
![Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58641.jpg&w=3840&q=50)
Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
Published on: November 9, 2018
Factors affecting ¹⁸F FDOPA standardized uptake value in patients with primary brain tumors after treatment
Agostino Chiaravalloti1, Alessandro Fiorentini1, Veronica Villani2
1Department of Biomedicine and Prevention, University Tor Vergata of Rome, Italy.
Aim:
To investigate the factors affecting (18)F FDOPA uptake in patients with primary brain tumors (PBT) after treatment.
Materials And Methods:
97 patients with PBT (6 were grade I, 40 were grade II, 29 were grade III and 22 were grade IV) underwent (18)F FDOPA positron emission tomography/computed tomography (PET/CT) after treatment. Intervals from surgery, chemotherapy (CHT) and radiotherapy (RT) were 41.48 (±42.27), 16.04 (±29.08) and 28.62 (±34.49) months respectively.
Results:
(18)F FDOPA uptake in the site of recurrence was not related to the interval from surgery and CHT while a significant relationship has been found with the interval from RT and tumor grade.
Conclusions:
The results of our study show that the interval from RT and the grade of PBT should be considered carefully when evaluating brain PET/CT scans since these factors could directly affect (18)F FDOPA uptake.
