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Updated: Apr 18, 2026
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Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source
Published on: May 29, 2021
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Physical sciences at Diamond: past achievements and future opportunities
1London Centre for Nanotechnology, University College London, London WC1H 0AJ, UK d.mcmorrow@ucl.ac.uk.
Summary
The Diamond Light Source began user operations in 2007, providing UK scientists with advanced X-ray beam capabilities. This facility offers unique opportunities, advancing physical sciences research within the UK.
Area of Science:
- Physical Sciences
- Materials Science
- Chemistry
- Biology
Background:
- The UK lacked access to third-generation synchrotron light sources prior to 2007.
- International facilities provided advanced X-ray capabilities, but unique resources were limited.
- The establishment of Diamond Light Source aimed to bridge this gap.
Purpose of the Study:
- To review the achievements of the Diamond Light Source since its user operation began.
- To highlight the unique capabilities and scientific advancements enabled by the facility.
- To outline potential future opportunities for research.
Main Methods:
- Utilizing ultra-bright X-ray beams from a third-generation synchrotron source.
- Providing routine access to advanced experimental techniques for the UK scientific community.
- Leveraging unique facility capabilities for novel research.
Main Results:
- Significant advancements in physical sciences research across various disciplines.
- Successful routine delivery of high-quality X-ray beams to users.
- Establishment of unique experimental capabilities not available elsewhere.
Conclusions:
- Diamond Light Source represents a major milestone for UK physical sciences.
- The facility has successfully provided world-class research infrastructure.
- Future opportunities promise continued innovation and discovery.
