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Liver-cell adenoma in an epileptic man on barbiturates
1Department of Pathology, University of Navarra, Pamplona, Spain.
Histology and Histopathology
|July 1, 1989
Abstract:
The case of a 19-year-old epileptic man with a solitary hepatic adenoma is described. The tumor was 9 x 8.5 x 6.5 cm in size and microscopically consisted of cells similar in appearance to non-neoplastic hepatocytes, arranged in cords with slit-like sinusoids interposed. Bile ducts and portal tracts were conspicuously absent. Our patient was on antiepileptic drugs, among them phenobarbital which experimentally produces liver cell tumors in mice and rats.