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Estimation of salivary β-glucuronidase activity as a marker of periodontal disease: A case control study
Chandra Sekhara Prabhahar1, K Thanvir Mohamed Niazi2, R Prakash3
1Department of Periodontology, Best Dental Science College, Madurai, India.
Aim:
The aim of the present study was to estimate the salivary β-glucuronidase level in healthy and diseased periodontium and to correlate the level with clinical measurement.
Materials And Methods:
70 patients were included in this study with the age ranging from 30 to 65 years. Both males and females were included. They were divided into two groups: Control having healthy periodontium (n = 20) and experimental having diseased periodontium (n = 50). The parameters recorded were probing pocket depth, probing attachment level, gingival index, β-glucuronidase activity in the saliva, number of white blood cells, neutrophils, lymphocytes count, and platelet count.
Results:
It was observed that there was an increase in the level of salivary β-glucuronidase in the experimental subjects than in the control patients, and a significant positive linear relationship existed between salivary β-glucuronidase level and probing pocket depth in the experimental group.
Conclusion:
Level of salivary β-glucuronidase increases during inflammation in the periodontium.
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