[The pulsatile administration of LHRH in the differential diagnosis of hypogonadotropic hypogonadism]

The results of the pulsating administration of LHRH (APLHRH) using a portable infusion pumps of national fabrication (TECENSA-AIP-GZ) at doses of 18.2 mcq every 90 min., via subcutanea, in abdominal anterior wall are presented. This was carried out in order to localise the hypogonadotropic hypogonadism. There were statistically significant differences between the group of hypothalamic origin and that of hypophyseal origin after the APLHRH administration. In the first group named, the response patterns of LH and FSH were similar to those obtained in adults, while in the second group there was no response. These differences were not observed at basal conditions nor with acute stimuli of LHRH. We concluded, highlighting the efficacy of this test to diagnose the different types of hypogonadotropic hypogonadism.