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Updated: Apr 18, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
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Optical innovations in surgery.

E de Boer1, N J Harlaar, A Taruttis

  • 1Department of Surgery, Groningen, The Netherlands; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.

The British Journal of Surgery
|January 29, 2015
PubMed
Summary
This summary is machine-generated.

Optical imaging offers real-time feedback for surgeons, improving tumor detection and margin assessment in cancer surgery. This technology aids in achieving negative margins and detecting micrometastatic disease, enhancing patient prognosis.

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Area of Science:

  • Surgical Oncology
  • Medical Imaging
  • Theranostics

Background:

  • Significant advancements in optical and fluorescence imaging for surgical translation.
  • Fluorescence imaging provides real-time intraoperative feedback for identifying tumor margins.
  • Potential for intraoperative adjuvant treatments like photoimmunotherapy.

Purpose of the Study:

  • To review the application of optical imaging in intraoperative guidance and decision-making.
  • To highlight the role of image-guided surgery in improving patient outcomes.

Main Methods:

  • Review of current literature on optical imaging in surgery.
  • Discussion of fluorescence imaging, photoimmunotherapy, and multispectral optoacoustic tomography.

Main Results:

  • Image-guided cancer surgery shows potential for enhanced surgical care.
  • Photoimmunotherapy emerges as a promising theranostic approach for residual disease treatment.
  • Multispectral optoacoustic tomography shows potential for perioperative and postoperative applications.

Conclusions:

  • Real-time optical imaging strategies have advanced for intraoperative tumor detection and margin assessment.
  • Optical imaging promises higher rates of negative surgical margins and early detection of micrometastatic disease.