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Gold-naproxen pneumonitis. A toxic drug interaction?
R G McFadden1, L J Fraher, J M Thompson
1Department of Medicine, Lawson Research Institute of St. Joseph's Health Centre, London, Canada.
Chest
|July 1, 1989
Abstract:
A patient with rheumatoid arthritis developed restrictive lung disease and blood eosinophilia. Gold pneumonitis was suspected but the patient did not improve until naproxen was discontinued as well. Lymphocyte transformation studies suggested hypersensitivity to gold. We hypothesize that naproxen unmasked and perpetuated the manifestations of gold hypersensitivity in our patient.