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Updated: Apr 18, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
[Alcohol consumption after liver transplantation in patients transplanted for alcoholic cirrhosis]
Hélène Donnadieu-Rigole1, Pascal Perney2, Georges-Philippe Pageaux3
1CHRU de Montpellier, hôpital Saint-Éloi, service de médecine interne et addictologie, rue Augustin-Fliche, 34000 Montpellier, France; Université Montpellier I, 34000 Montpellier, France; U844 Inserm, hôpital Saint-Éloi, 34000 Montpellier, France.
Abstract:
Liver transplantation is the gold standard treatment for terminal cirrhosis and liver cancer (if no surgical option is available). In France, the leading cause of liver transplantation is alcoholic cirrhosis. Severe alcohol relapse is often considered as a failure and concerns 11 to 26% of cases. The severe relapse causes a significant decrease in survival after 5 years of follow up, regardless of the origin of the transplantation. Predictors of relapse, like pretransplant abstinence duration, additional psychiatric co-morbidity, age, and level of social support have been assessed. However, alcohol addiction and liver transplantation are complex entities that cannot be reduced to a list of predictive factors. A multidisciplinary approach including an addiction specialist should identify and minimize the risk of severe relapse.
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