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Factors affecting pancreatic hyperamylasemia in patients undergoing peroral single-balloon enteroscopy
Tomoyuki Tsujikawa1, Shigeki Bamba2, Osamu Inatomi2
1Comprehensive Internal Medicine, Shiga University of Medical Science, Otsu, Japan.
Background And Aim:
Acute pancreatitis following balloon-assisted enteroscopy is a rare but serious complication. The causative mechanism is uncertain and prevention strategies are not established. We conducted a retrospective study to clarify the risk factors for pancreatic hyperamylasemia.
Methods:
Eighty-four patients undergoing peroral single-balloon enteroscopy (SBE) were enrolled in this study. Serum pancreatic and salivary amylase levels were measured 2 h after endoscopic examination.
Results:
We experienced three patients with post-SBE pancreatitis. Factors predicting pancreatic hyperamylasemia were: (i) elderly patients; (ii) deeper insertion; and (iii) clockwise insertion. In contrast, younger age at examination was a significant factor observed in salivary hyperamylasemia.
Conclusions:
It is important to measure pancreatic amylase and not total amylase after SBE. When carrying out peroral SBE, the distance of insertion should be reduced especially if the scope traces a clockwise loop or the subject is elderly.
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