Related Experiment Video
Updated: Apr 18, 2026

06:29
Novel Surgical Rodent Model for Studying Neuroma Pain Treatment Options using Targeted Muscle Reinnervation Through the Saphenous Nerve
Published on: November 14, 2025
265
Percutaneous tibial nerve stimulation and sacral neuromodulation: an update
Priyanka Gupta1, Michael J Ehlert, Larry T Sirls
1Female Pelvic Medicine and Reconstructive Surgery, Beaumont Health System, 3535 W. 13 Mile Road, Ste. 438, Royal Oak, MI, 48073, USA, Priyanka.Gupta@beaumont.edu.
Current Urology Reports
|January 30, 2015
Summary
Neuromodulation, including percutaneous tibial nerve stimulation (PTNS) and sacral neuromodulation (SNM), offers effective treatment for pelvic floor disorders. This review explores the latest advancements, benefits, and drawbacks of these innovative therapies.
Area of Science:
- Urology
- Neurology
- Gynecology
Background:
- Neuromodulation is a key treatment for pelvic floor disorders.
- Percutaneous tibial nerve stimulation (PTNS) and sacral neuromodulation (SNM) are approved neuromodulation therapies.
- These therapies address conditions such as overactive bladder, fecal incontinence, and pelvic pain.
Purpose of the Study:
- To review recent literature on PTNS and SNM for pelvic floor disorders.
- To discuss the advantages and limitations of both PTNS and SNM.
- To highlight recent innovations in neuromodulation therapies.
Main Methods:
- Review of current scientific literature on PTNS and SNM.
- Comparative analysis of efficacy, side effects, and patient experience.
- Discussion of technological advancements and future directions.
Main Results:
- PTNS is a minimally invasive, office-based treatment with minimal side effects but requires frequent visits.
- SNM utilizes an implanted device for S3 nerve root stimulation, offering symptom improvement for various pelvic floor disorders.
- Both methods demonstrate efficacy but differ in invasiveness, treatment schedule, and long-term management.
Conclusions:
- PTNS and SNM are valuable neuromodulation techniques for pelvic floor dysfunction.
- Patient selection and treatment preferences influence the choice between PTNS and SNM.
- Ongoing innovations promise to enhance the effectiveness and accessibility of neuromodulation treatments.

