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Lone bilateral blindness: a transient ischaemic attack.

M S Dennis1, J M Bamford, P A Sandercock

  • 1University Department of Clinical Neurology, Radcliffe Infirmary, Oxford.

Lancet (London, England)
|January 28, 1989
PubMed
Summary
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Patients experiencing sudden, temporary bilateral blindness face a significantly higher stroke risk. This condition warrants classification alongside transient ischemic attacks (TIAs) for prompt medical attention.

Area of Science:

  • Neurology
  • Ophthalmology
  • Vascular Neurology

Background:

  • The Oxfordshire Community Stroke Project investigated a cohort of patients with isolated bilateral visual disturbances.
  • This study focused on 'lone bilateral blindness,' characterized by sudden, simultaneous vision loss in both eyes lasting less than 24 hours, without other neurological symptoms.

Observation:

  • The study identified 14 patients with lone bilateral blindness.
  • These patients shared similar demographics and vascular risk factors with 184 patients presenting with transient ischemic attacks (TIAs).

Findings:

  • Over a mean follow-up of 2.4 years, 5 of the 14 patients (35.7%) experienced a first-ever stroke.
  • This represents a 16-fold increased risk of stroke compared to the expected rate.

Related Experiment Videos

Implications:

  • Lone bilateral blindness is a critical indicator of cerebrovascular disease.
  • Patients presenting with this symptom should be considered at high risk for stroke and managed under the diagnostic umbrella of transient ischemic attacks (TIAs).