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Australian Rotavirus Surveillance Program annual report, 2013
Carl D Kirkwood1, Susie Roczo-Farkas2,
1Senior Research Fellow, Murdoch Childrens Research Institute, Parkville, Victoria.
Communicable Diseases Intelligence Quarterly Report
|January 30, 2015
Summary
In 2013, G12P[8] became the leading rotavirus genotype causing hospitalizations in Australia. Rotavirus genotype distribution varied by age group and vaccine type used, highlighting ongoing changes post-vaccine introduction.
Area of Science:
- Virology
- Public Health
- Epidemiology
Background:
- Rotavirus is a leading cause of acute gastroenteritis in children globally.
- Vaccination programs have influenced rotavirus genotype circulation patterns.
- Continuous surveillance is crucial for monitoring changes in circulating rotavirus strains.
Purpose of the Study:
- To identify the predominant rotavirus genotypes causing hospitalizations in Australia during 2013.
- To analyze rotavirus genotype distribution by age group and geographical region.
- To assess the impact of different rotavirus vaccines on genotype prevalence.
Main Methods:
- Collection and analysis of 1,035 fecal samples for rotavirus G and P genotyping.
- Confirmation of 828 rotavirus-positive samples.
- Stratification of data by age (under 5 years vs. older children/adults) and vaccine type.
Main Results:
- G12P[8] was the dominant genotype nationally (33%), followed by G3P[8] (31%) and G2P[4] (14%).
- In children under 5, G3P[8] was dominant (39.2%), with G12P[8] second (31%).
- G12P[8] prevalence was higher in regions using RotaTeq, while G3P[8] was more common with Rotarix.
Conclusions:
- G12P[8] emerged as the primary cause of rotavirus disease in Australia in 2013.
- Rotavirus genotype distribution exhibits annual fluctuations and is influenced by vaccination strategies.
- Ongoing surveillance is essential to track evolving wild-type rotavirus populations post-vaccine introduction.
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