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Multiplex nucleic acid suspension bead arrays for detection and subtyping of filoviruses
Cecilia Bergqvist1, Petra Holmström2, Gunnel Lindegren2
1Public Health Agency of Sweden, Solna, Sweden Stockholm University, Stockholm, Sweden.
Journal of Clinical Microbiology
|January 30, 2015
Abstract:
Here we describe multiplex suspension bead array systems that allow fast and reliable detection of reverse transcriptase (RT) PCR amplified filovirus genomes and also enable subtyping of Ebola virus species and Marburg virus strains. These systems have an analytical sensitivity equivalent to that of RT-PCR.
