Related Experiment Video
Updated: Apr 18, 2026

Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
Published on: December 9, 2022
Laboratory Diagnosis of Sepsis? No SIRS, Not Just Yet
1bioMérieux, Inc., Durham, North Carolina, USA william.dunne@biomerieux.com.
Abstract:
In order to maximize the benefit of prompt antimicrobial therapy and avoid the risk associated with inappropriate use of antimicrobial agents, patients with suspected sepsis must be rapidly differentiated from patients with systemic inflammatory response syndrome (SIRS). In combination with standard microbiological testing, a number of biomarkers have been recently evaluated for this purpose, and the performance characteristics of the most promising of these are reviewed.
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