Related Experiment Videos
Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA
C J Brown1, S J Goss, D B Lubahn
1Department of Medical Genetics, University of Toronto, Ontario, Canada.
American Journal of Human Genetics
|February 1, 1989
Abstract:
The gene for the androgen receptor, mutations at which cause the X-linked androgen insensitivity syndrome, has been localized to the q11----q12 region of the human X chromosome by analysis, using a cloned cDNA for the androgen receptor, of somatic cell hybrid panels segregating portions of the X chromosome. A moderate-frequency HindIII RFLP has been found which should be useful in genetic linkage analysis of the various inherited forms of androgen insensitivity.