Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

1.7K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.7K
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

1.3K
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
1.3K
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

1.0K
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
1.0K
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

1.4K
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
1.4K
Esophageal Achalasia01:27

Esophageal Achalasia

3
Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide...
3
Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

2.2K
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Multinational, Retrospective, Real-World Study: Treatment Patterns in Patients With HER2-Positive Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Beyond First-line in East Asia (HER2+ GASTA Study).

Cancer research and treatment·2026
Same author

Knowledge Gaps, Treatment Preferences, and Unmet Clinical Needs Among Patients With Inflammatory Bowel Disease: A Cross-Sectional Study.

The Kaohsiung journal of medical sciences·2026
Same author

Sebivo Ameliorated Fibrotic and Inflammatory Changes in Kidney and Heart in Animal Model of Chronic Kidney Disease.

Nephrology (Carlton, Vic.)·2026
Same author

Incidental Appendiceal Mucocele in a Patient with Ulcerative Colitis.

Digestive diseases and sciences·2026
Same author

Taiwan practical consensus for evaluation and management of small-bowel bleeding.

Journal of the Chinese Medical Association : JCMA·2026
Same author

Very Early Biologic Therapy within Six Months of Crohn's Disease Diagnosis Improves One-Year Steroid-Free Clinical Remission: A Retrospective Cohort Study.

Digestion·2026

Related Experiment Video

Updated: Apr 18, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
06:55

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging

Published on: May 11, 2014

12.5K

Benign esophageal lesions: endoscopic and pathologic features.

Shu-Jung Tsai1, Ching-Chung Lin1, Chen-Wang Chang1

  • 1Shu-Jung Tsai, Ching-Chung Lin, Chen-Wang Chang, Chien-Yuan Hung, Tze-Yu Shieh, Horng-Yuan Wang, Shou-Chuan Shih, Ming-Jen Chen, Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei 10001, Taiwan.

World Journal of Gastroenterology
|January 30, 2015
PubMed
Summary

This review details benign esophageal lesions, aiding physicians in diagnosis and management. Understanding endoscopic and pathologic features is key for effective treatment of these common gastrointestinal findings.

Keywords:
Benign tumorEndoscopyEpithelial lesionsEsophagusSubepithelial lesions

More Related Videos

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.7K
Robotic Enucleation of Esophageal Leiomyoma
04:19

Robotic Enucleation of Esophageal Leiomyoma

Published on: February 20, 2026

445

Related Experiment Videos

Last Updated: Apr 18, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
06:55

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging

Published on: May 11, 2014

12.5K
Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.7K
Robotic Enucleation of Esophageal Leiomyoma
04:19

Robotic Enucleation of Esophageal Leiomyoma

Published on: February 20, 2026

445

Area of Science:

  • Gastroenterology
  • Pathology
  • Endoscopy

Background:

  • Benign esophageal lesions present diverse clinical and pathological characteristics.
  • Accurate identification and management of these lesions are crucial for patient care.
  • Endoscopic and pathological features are key to diagnosis and treatment strategies.

Purpose of the Study:

  • To provide updated features of benign esophageal lesions for improved physician management.
  • To review endoscopic findings to aid in the detection and differential diagnosis of esophageal lesions.
  • To guide appropriate clinical decisions regarding the management of various benign esophageal conditions.

Main Methods:

  • Review of endoscopic features from 2997 patients.
  • Analysis of epithelial and subepithelial lesion frequencies.
  • Correlation of endoscopic appearance with biopsy findings.

Main Results:

  • Epithelial lesions ordered by frequency: glycogenic acanthosis, heterotopic gastric mucosa, squamous papilloma, hyperplastic polyp, ectopic sebaceous gland, xanthoma.
  • Subepithelial lesions ordered by frequency: hemangioma, leiomyoma, dysphagia aortica, granular cell tumor.
  • Most lesions diagnosed via endoscopy and biopsy; submucosal lesions by endoscopic resection.

Conclusions:

  • Endoscopic appearance and biopsy are vital for diagnosing most benign esophageal lesions.
  • Management depends on diagnostic certainty and symptom presence.
  • Endoscopic resection is recommended for granular cell tumors and squamous papillomas due to rare malignant potential. Dysphagia aortica is a consideration in elderly dysphagia patients.