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Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
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Related Experiment Video

Updated: Apr 18, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
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First MRI application of an active breathing coordinator.

E Kaza1, R Symonds-Tayler, D J Collins

  • 1CR-UK Cancer Imaging Centre, Institute of Cancer Research London and Royal Marsden Hospital, London, UK.

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|January 31, 2015
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Summary
This summary is machine-generated.

A novel adaptation of the Active Breathing Coordinator (ABC) for Magnetic Resonance Imaging (MRI) enables precise breath-holding for thoracic and abdominal scans. This integration improves organ position reproducibility and enhances radiotherapy planning with advanced MRI sequences.

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Area of Science:

  • Medical Imaging
  • Radiotherapy Technology
  • Respiratory Monitoring

Background:

  • Active Breathing Coordinator (ABC) devices are used to control respiration during medical imaging.
  • Magnetic Resonance Imaging (MRI) requires motion management for optimal image quality, especially in the thorax and abdomen.
  • Integrating respiratory control with MRI can enhance diagnostic accuracy and treatment planning.

Purpose of the Study:

  • To adapt a commercial Active Breathing Coordinator (ABC) device for Magnetic Resonance Imaging (MRI) use.
  • To assess the feasibility and advantages of using the MR-compatible ABC for thoracic and abdominal examinations.
  • To evaluate the reproducibility of organ position and inter-modality registration for radiotherapy planning.

Main Methods:

  • A commercial ABC device was modified and adapted for MRI compatibility.
  • Automatic MRI acquisition was synchronized with ABC-controlled breath holds.
  • Feasibility was demonstrated in healthy volunteers and lung cancer patients.
  • MR-CT registration was assessed using identical ABC settings.

Main Results:

  • Successful adaptation and integration of the ABC device with MRI.
  • Demonstrated feasibility of MR-ABC for thoracic and abdominal imaging.
  • High intra-session reproducibility of organ position in lung cancer patients.
  • Good MR-CT inter-modality registration achieved.

Conclusions:

  • The adapted ABC device is feasible for MRI, enabling precise breath-holding.
  • MR-ABC improves organ position reproducibility, crucial for radiotherapy planning.
  • The combination of MRI's contrast mechanisms with ABC control offers superior diagnostic information compared to CT.