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In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis
Published on: June 8, 2022
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Adult necrotising enterocolitis: a rare entity
Mahesh Gupta1, Subhash Goyal, Milan Verma
1Department of Surgery, M.M. Institute of Medical Sciences and Research, Mullana, (Distt - Ambala), Haryana, India.
Acta Medica Indonesiana
|January 31, 2015
Summary
Adult Necrotising Enterocolitis can mimic intestinal obstruction, necessitating prompt intervention. This case highlights the condition's poor prognosis despite surgical efforts, emphasizing the need for early diagnosis in adults.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Abdominal Surgery
Background:
- Adult Necrotising Enterocolitis (ANEC) is a rare but severe gastrointestinal emergency.
- It often presents with symptoms mimicking mechanical intestinal obstruction, posing diagnostic challenges.
Observation:
- A case report of an adult female diagnosed with intestinal obstruction is presented.
- Exploratory laparotomy revealed extensive gangrene of the small bowel, caecum, and proximal ascending colon, without an identifiable mechanical cause.
- Surgical resection of the affected bowel was performed, followed by jejunostomy and transverse colostomy.
Findings:
- The patient did not survive the postoperative period, indicating a poor outcome.
- ANEC can present insidiously, making early clinical and radiological differentiation from mechanical obstruction difficult.
Implications:
- Prompt medical and surgical intervention is crucial in suspected cases of ANEC, even with ambiguous presentations.
- This case underscores the critical importance of considering ANEC in the differential diagnosis of adult intestinal obstruction.
- Further research into the pathophysiology and management of ANEC in adults is warranted to improve patient survival rates.
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