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Super-resolution Fluorescence Microscopy

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...

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Related Experiment Video

Updated: Apr 18, 2026

Micron-scale Resolution Optical Tomography of Entire Mouse Brains with Confocal Light Sheet Microscopy

Micron-scale Resolution Optical Tomography of Entire Mouse Brains with Confocal Light Sheet Microscopy

Published on: October 8, 2013

Microscopy. The superresolved brain

Hans-Ulrich Dodt¹

¹Vienna University of Technology, 1040 Vienna, Austria, and Medical University of Vienna, 1090 Vienna, Austria. dodt@tuwien.ac.at.

Science (New York, N.Y.)

|January 31, 2015

Summary

No abstract available in PubMed .

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Last Updated: Apr 18, 2026

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