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Updated: Apr 18, 2026

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Published on: May 11, 2016

Skin squamous cell carcinoma presenting as cellulitis.

Min Zhao¹, Katamreddy Sasikumar¹, Masanosuke Kinoshita¹

¹Internal Medicine, Montefiore Mount Vernon Hospital, Mount Vernon, NY, USA.

Clinical Medicine Insights. Case Reports

|January 31, 2015

Summary

Skin squamous cell carcinoma (SCC) can mimic cellulitis. A facial cellulitis case unresponsive to antibiotics was diagnosed as newly discovered SCC via biopsy, highlighting the need for biopsy in persistent cases.

Keywords:

cellulitis presentation squamous cell carcinoma

Related Experiment Videos

Last Updated: Apr 18, 2026

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Published on: May 11, 2016

Area of Science:

Dermatology
Oncology

Background:

Skin squamous cell carcinoma (SCC) typically presents as erythematous or pigmented papules/plaques that can ulcerate.
Metastatic SCC causing cellulitis is rare, with only one prior report.

Observation:

A patient presented with facial cellulitis that was unresponsive to a full course of antibiotic treatment.
The persistent cellulitis was investigated further.

Findings:

Biopsy revealed the patient had a newly diagnosed squamous cell carcinoma (SCC).
This case suggests SCC can present atypically as cellulitis.

Implications:

Malignancy should be considered in unusual presentations of cellulitis.
Biopsy is crucial for patients with cellulitis who do not improve with standard antibiotic therapy.