Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Automated Microbial Diagnostics

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Preparing pathology for personalized medicine: possibilities for improvement of the pre-analytical phase.

Histopathology·2011

Same author

A surprising method for green extraction of essential oil from dry spices: Microwave dry-diffusion and gravity.

Journal of chromatography. A·2010

Same author

New and rapid analytical procedure for water content determination: microwave accelerated Dean-Stark.

Analytica chimica acta·2008

Same author

Microwave-integrated extraction of total fats and oils.

Journal of chromatography. A·2008

Same author

Green procedure with a green solvent for fats and oils' determination. Microwave-integrated Soxhlet using limonene followed by microwave Clevenger distillation.

Journal of chromatography. A·2008

Same author

Microwave hydrodiffusion and gravity, a new technique for extraction of essential oils.

Journal of chromatography. A·2008

Search research articles

Related Experiment Video

Updated: Apr 18, 2026

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Published on: June 23, 2022

Towards the lean lab: the industry challenge.

Franco Visinoni¹

¹Milestone Srl, Via Fatebenefratelli 1/5, 24010, Sorisole Bergamo, Italy, f.visinoni@milestonemedsrl.com.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer

|February 1, 2015

Summary

This summary is machine-generated.

Standardizing pre-analytic processes in anatomic pathology is crucial. Implementing scientifically validated guidelines and a documented chain of custody improves specimen quality and diagnostic accuracy for clinicians and patients.

More Related Videos

Measuring Lactase Enzymatic Activity in the Teaching Lab

Measuring Lactase Enzymatic Activity in the Teaching Lab

Published on: August 6, 2018

A Small-Scale Setup for Algal Toxicity Testing of Nanomaterials and Other Difficult Substances

A Small-Scale Setup for Algal Toxicity Testing of Nanomaterials and Other Difficult Substances

Published on: October 10, 2020

Related Experiment Videos

Last Updated: Apr 18, 2026

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Published on: June 23, 2022

Measuring Lactase Enzymatic Activity in the Teaching Lab

Measuring Lactase Enzymatic Activity in the Teaching Lab

Published on: August 6, 2018

A Small-Scale Setup for Algal Toxicity Testing of Nanomaterials and Other Difficult Substances

A Small-Scale Setup for Algal Toxicity Testing of Nanomaterials and Other Difficult Substances

Published on: October 10, 2020

Area of Science:

Anatomic Pathology
Laboratory Diagnostics
Molecular Pathology

Background:

Pre-analytic processes in anatomic pathology are largely uncontrolled and inconsistently performed.
Defects in pre-analytic workflows contribute to nearly 75% of laboratory diagnostic errors.
Quality surveys reveal significant issues with patient/tissue identity and specimen preservation.

Purpose of the Study:

To describe historical tissue processing methods and identify current global laboratory practice gaps.
To propose methodological and technological solutions for pre-analytic process improvement.
To emphasize the need for scientifically validated specimen guidelines and a standardized chain of custody.

Main Methods:

Review of historical tissue processing approaches.
Analysis of worldwide observations in current laboratory practices.
Identification of potential solutions and process improvements.

Main Results:

Current pre-analytic practices lack standardization, leading to diagnostic errors.
Opportunities exist to optimize specimen collection, handling, and fixation for molecular studies.
Standardization can improve specimen quality, diagnostic accuracy, and turnaround times.

Conclusions:

A scientifically validated, standardized "chain of custody" for pre-analytic steps is essential.
Optimizing pre-analytic processes enhances specimen suitability for molecular testing.
Improvements lead to more accurate results, reduced turnaround times, and increased clinician/patient satisfaction.