Related Experiment Video
Updated: Apr 18, 2026

Noninvasive Monitoring of Lesion Size in a Heterologous Mouse Model of Endometriosis
Published on: February 26, 2019
On-label and off-label drug use in the treatment of endometriosis
Alexander M Quaas1, Elizabeth A Weedin1, Karl R Hansen1
1Section of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Abstract:
Endometriosis, characterized by the presence of endometrial glands and stroma in extrauterine locations, is a significant cause of pelvic pain and infertility, as well as a major health care burden. Although Food and Drug Administration (FDA)-approved treatments are available, the use of "off-label" medications for endometriosis is widespread. In this review, we provide an overview of the current FDA-approved treatments, followed by a detailed review of the major "off-label" treatments being used in the United States and worldwide, including efficacy, side effects, drug interactions, contraindications, and anomaly risks.
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