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Bone mineral density in juvenile onset systemic lupus erythematosus
R Abdwani1, E Abdulla, S Yaroubi
1Departments of Child Health, *Radiology and #Pharmacology and Clinical Pharmacy, Sultan Qaboos University Hospital, Muscat, Oman. Correspondence to: Dr Reem Abdwani, Senior Consultant Pediatric Rheumatologist, Sultan Qaboos University Hospital, Muscat, Oman. reemabd@hotmail.com.
Objective:
To compare bone mineral density in patients with juvenile-onset Systemic lupus erythematosus and healthy controls.
Participants:
Serial bone mineral density measurements in 27 patients with juvenile-onset systemic lupus were compared to 97 healthy age-matched controls.
Results:
All patients with juvenile-onset had low bone mineral density scores at initial assessment that progressed over disease course. Low body mass index was independently associated with a decline in bone mineral density Z scores; disease activity, use of immunosuppressive agents and vitamin D levels were not risk factors.
Conclusions:
Patients with juvenile-onset systemic lupus erythematosus have low bone mineral density.
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