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Malignant rhabdoid tumor of kidney and brain in an infant
Deepti Shukla1, Aditya Pradhan, Mukesh Bhardwaj
1Departments of Histopathology and *Urosurgery, BLK Hospital, Pusa Road, New Delhi, India. Correspondence to: Dr Veena Malhotra, Histopathology Department, BLK Hospital, Pusa Road, New Delhi, India. veena.malhotra@blkhospital.com.
Background:
Malignant rhabdoid tumors of kidney are associated with atypical teratoid rhabdoid tumors of brain, both being characterized genetically by deletion/ mutation of SMAR CBI/ INI gene.
Case Characteristics:
6-month-old male presented with a brain tumor and was subsequently found to have malignant rhabdoid tumor of kidney.
Interventions:
Surgical resection of brain tumor followed by chemotherapy and subsequently resection of renal tumor.
Outcome:
Child died seven months after initial presentation.
Message:
Children presenting with embroynal brain tumor, should be investigated for renal tumors and vice versa.
Message:
Children presenting with embroynal brain tumor, should be investigated for renal tumors and vice versa.
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