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Updated: Apr 18, 2026

Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Cord blood vitamin D levels of term neonates
K Devaraj Naik1, Remesh Preetha, A M Ramachandran
1Malabar Institute of Medical sceinces, Calicut, Kerala, India. amr2003in@yahoo.co.in.
Insights
Most Indian neonates are born with vitamin D deficiency, even in tropical regions. This study highlights the need for monitoring vitamin D levels in newborns.
Area of Science:
- Neonatal Health
- Nutritional Biochemistry
Background:
- Vitamin D is crucial for infant health.
- Deficiency is a global concern, but data from tropical regions like India is limited.
Purpose of the Study:
- To determine the prevalence of vitamin D deficiency in newborns in Kozhikode, Kerala, India.
- To assess cord blood 25-hydroxy vitamin D levels in healthy term neonates.
Main Methods:
- Cord blood samples were collected from 50 healthy term neonates.
- 25-hydroxy vitamin D levels were measured.
- Data was analyzed for distribution and prevalence.
Main Results:
- The mean vitamin D level was 11.36 (4.75) ng/mL.
- The median level was 10.85 ng/mL (range: 3.9-24.9 ng/mL).
- Most neonates (majority) had levels between 5 to 15 ng/mL, indicating widespread deficiency.
Conclusions:
- A significant proportion of neonates in this tropical Indian region are born with vitamin D deficiency.
- Findings suggest potential public health implications for maternal and infant vitamin D status.
Abstract:
We estimated cord blood 25-hydroxy vitamin D levels of 50 term healthy neonates born in a tertiary care center of Kozhikode, Kerala, India. Vitamin D levels were normally distributed with a mean (SD) value of 11.36 (4.75) ng/mL and median (range) values of 10.85 (3.9-24.9) ng/mL. Majority of babies had values between 5 to 15 ng/mL. This study shows that even in tropical climates most of our neonates are born with deficient vitamin D levels.
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