Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depression: Overview01:18

Depression: Overview

1.2K
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
1.2K
Long-term Depression01:05

Long-term Depression

33.9K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.9K
Long-term Depression01:03

Long-term Depression

3.6K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.6K
Stress and Mental Health01:30

Stress and Mental Health

1.5K
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
1.5K
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

1.2K
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
1.2K
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

883
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
883

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"Clinical Burnout": A Diagnosis in Search of Validation.

Journal of occupational and environmental medicine·2026
Same author

The Occupational Depression Inventory performs well in Norway.

Scientific reports·2026
Same author

Reducing Job-Related Distress to "Burnout" Raises Concerns.

Workplace health & safety·2026
Same author

Validation of the Swedish Version of the Occupational Anxiety Inventory.

Stress and health : journal of the International Society for the Investigation of Stress·2026
Same author

Free Association Database for a 62-Word Dataset Including Emotion and Colour Terms in English, Estonian, French, German, Italian, Lithuanian, and Spanish: Data from 14 Countries.

Journal of open psychology data·2025
Same author

On mischaracterizations of the Occupational Depression Inventory.

Work (Reading, Mass.)·2025

Related Experiment Video

Updated: Apr 18, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

1.3K

Burnout-depression overlap: a review.

Renzo Bianchi1, Irvin Sam Schonfeld2, Eric Laurent1

  • 1University of Franche-Comté, Besançon, France.

Clinical Psychology Review
|February 2, 2015
PubMed
Summary
This summary is machine-generated.

Burnout and depression overlap is debated. Current research suggests their distinction is fragile, with inconsistent evidence supporting burnout as a separate phenomenon from depression.

Keywords:
BurnoutDepressionDepressive disordersDifferential diagnosisReviewStress

More Related Videos

Mindfulness in Motion MIM: An Onsite Mindfulness Based Intervention MBI for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement
12:22

Mindfulness in Motion MIM: An Onsite Mindfulness Based Intervention MBI for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement

Published on: July 1, 2015

24.8K
Burn Injury-Induced Pain and Depression-Like Behavior in Mice
07:08

Burn Injury-Induced Pain and Depression-Like Behavior in Mice

Published on: September 29, 2021

3.8K

Related Experiment Videos

Last Updated: Apr 18, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

1.3K
Mindfulness in Motion MIM: An Onsite Mindfulness Based Intervention MBI for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement
12:22

Mindfulness in Motion MIM: An Onsite Mindfulness Based Intervention MBI for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement

Published on: July 1, 2015

24.8K
Burn Injury-Induced Pain and Depression-Like Behavior in Mice
07:08

Burn Injury-Induced Pain and Depression-Like Behavior in Mice

Published on: September 29, 2021

3.8K

Area of Science:

  • Psychiatry
  • Occupational Health
  • Psychology

Background:

  • The distinction between burnout and depression remains a controversial topic in scientific literature.
  • Existing research presents conflicting evidence regarding their separateness.

Purpose of the Study:

  • To conduct an up-to-date literature review on the overlap between burnout and depression.
  • To critically evaluate the conceptual and empirical evidence for burnout-depression distinctiveness.

Main Methods:

  • Systematic literature search across PubMed, PsycINFO, and IngentaConnect databases.
  • Inclusion of 92 studies relevant to the burnout-depression overlap issue.

Main Results:

  • The conceptual distinction between burnout and depression is found to be fragile.
  • Empirical evidence for burnout's distinctiveness is inconsistent, with recent studies questioning it.
  • Lack of consensus on diagnostic criteria for burnout and inadequate consideration of depressive disorder heterogeneity hinder resolution.

Conclusions:

  • The validity of the established burnout definition is questioned.
  • Future research should prioritize systematic clinical observation to clarify the burnout-depression relationship.