Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthetic Biology02:55

Synthetic Biology

5.8K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.8K
Bioreactor Controls-III01:22

Bioreactor Controls-III

57
Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...
57
Biosynthesis in Bacteria01:24

Biosynthesis in Bacteria

1.0K
Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
1.0K
Designing Growth Media for Bioreactors01:30

Designing Growth Media for Bioreactors

67
Growth media provide essential nutrients that support cell growth and metabolism, thereby enhancing the yield of valuable products such as enzymes, antibiotics, and biomass. Designing an effective growth medium involves balancing all components to prevent nutrient limitations or toxic excesses, both of which can impair growth and reduce product yields.Composition of a Typical Growth MediumA typical growth medium contains carbon and nitrogen sources, salts, vitamins, trace elements, and...
67
Upstream Processing01:27

Upstream Processing

89
Upstream processing represents a critical phase in biomanufacturing, wherein biological systems such as microorganisms, mammalian cells, or insect cells are cultivated to produce therapeutic proteins, vaccines, enzymes, or other biologically derived products. This phase encompasses all steps from the selection and genetic manipulation of the production organism to the cultivation of cells in bioreactors under tightly controlled environmental conditions.Host Selection and Genetic OptimizationThe...
89
The Central Dogma01:20

The Central Dogma

35.9K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
35.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis and control of untemplated DNA polymerase activity for guided synthesis of kilobase-scale DNA sequences.

Nature communications·2026
Same author

GENOME ENGINEERING. The Genome Project-Write.

Science (New York, N.Y.)·2016
See all related articles

Related Experiment Video

Updated: Apr 18, 2026

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
10:28

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

9.7K

Designer life using synthetic biology.

Andrew Hessel

    Science Progress
    |February 3, 2015
    PubMed
    Summary

    This article introduces synthetic biology, the design of living organisms. It explores current trends and future possibilities for those new to this rapidly advancing scientific field.

    Area of Science:

    • Synthetic Biology
    • Genetic Engineering
    • Bioengineering

    Background:

    • Synthetic biology is an emerging field focused on designing and constructing new biological parts, devices, and systems.
    • Understanding the fundamental principles of synthetic biology is crucial for innovation in life sciences.

    Purpose of the Study:

    • To provide an introductory overview of synthetic biology for newcomers.
    • To examine current trends and future prospects in the field of designing living systems.

    Main Methods:

    • Conceptual review of synthetic biology principles.
    • Analysis of current research and development trajectories.
    • Exploration of future applications and potential impact.

    Main Results:

    More Related Videos

    A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression
    11:23

    A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

    Published on: October 6, 2019

    10.9K
    Automated Robotic Liquid Handling Assembly of Modular DNA Devices
    11:22

    Automated Robotic Liquid Handling Assembly of Modular DNA Devices

    Published on: December 1, 2017

    13.0K

    Related Experiment Videos

    Last Updated: Apr 18, 2026

    Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
    10:28

    Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

    Published on: March 9, 2017

    9.7K
    A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression
    11:23

    A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

    Published on: October 6, 2019

    10.9K
    Automated Robotic Liquid Handling Assembly of Modular DNA Devices
    11:22

    Automated Robotic Liquid Handling Assembly of Modular DNA Devices

    Published on: December 1, 2017

    13.0K
    • Synthetic biology offers a framework for rational design of biological functions.
    • The field is rapidly evolving with significant potential for diverse applications.
    • Pointers for further learning and engagement are provided.

    Conclusions:

    • Synthetic biology represents a paradigm shift in biological sciences, enabling the engineering of life.
    • This introductory guide serves as a starting point for exploring this vast and largely uncharted territory.