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Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
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Rational drug product design integrates knowledge of the drug’s physicochemical properties, formulation components, manufacturing techniques, and intended route of administration. Each factor influences the drug’s performance, including how it is released, absorbed, and eliminated in the body.The physicochemical properties of a drug—such as solubility, stability, and particle size—affect its compatibility with excipients and the choice of dosage form. Excipients, though...
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Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
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Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
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Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Corrigendum: Core competencies for pharmaceutical physicians and drug development scientists.

Honorio Silva1, Peter Stonier1, Fritz Buhler1

  • 1International Federation of Associations of Pharmaceutical Physicians and Pharmaceutical Medicine, Special Secretariat Service Woerden, Netherlands.

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PubMed
Summary

This is a correction notice for a previously published article. It does not contain new scientific findings or data to summarize.

Keywords:
competency based educationcore competenciescorrigendumdrug development scientistslearning outcomesmedicines developmentpharmaceutical medicinepharmaceutical physicians

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Area of Science:

  • Correction Notice
  • Article Errata

Context:

  • This entry serves as a correction to a previously published article.
  • The correction pertains to specific details on page 105 of volume 4.

Purpose:

  • To ensure the accuracy and integrity of the scientific record.
  • To provide readers with the correct information for article PMID: 23986704.

Summary:

  • A correction has been issued for an article previously published in volume 4.
  • The errata specifically addresses content on page 105.

Impact:

  • Ensures readers have access to the accurate version of the research.
  • Maintains the reliability of scientific literature and citation accuracy.