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Updated: Apr 18, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Utilization of AngioVac and snare for eradication of a mobile right atrial thrombus
Joshua C Grimm1, Anahita M Parsee1, Jeffrey A Brinker2
1Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, Maryland.
Insights
Central venous catheters can increase the risk of right atrial thrombus. A novel approach using the AngioVac Aspiration System and snare catheterization successfully removed a complex thrombus unresponsive to medical therapy.
Area of Science:
- Cardiology
- Interventional Radiology
Background:
- Right atrial thrombus formation is associated with central venous catheter use.
- Management strategies depend on clot characteristics and patient factors.
- Thrombolytic therapy may be insufficient for chronic or adherent thrombi, posing embolic risks.
Observation:
- A patient presented with a right atrial thrombus.
- The thrombus was deemed unsuitable for conventional thrombolytic therapy due to chronicity and adherence.
- This posed a significant risk of embolic events.
Findings:
- A combined approach utilizing the AngioVac Aspiration System and percutaneous snare catheterization was employed.
- This minimally invasive technique successfully removed the complex right atrial thrombus.
- Complete clot burden resolution was achieved without immediate embolic complications.
Implications:
- This case highlights a viable alternative for managing complex right atrial thrombi unresponsive to medical treatment.
- The AngioVac system offers a promising option for interventional cardiologists and radiologists.
- This approach may reduce the risk of embolic events in challenging thrombus cases.
Abstract:
Although there are multiple etiologies of a right atrial thrombus, the presence of a central venous catheter increases the risk for its development. Once diagnosed, an assessment of patient-specific factors will aid in dictating the appropriate management strategy. In cases of chronic disease or adherent thrombotic masses, thrombolytic therapy might not result in complete resolution of the clot burden and could lead to a devastating embolic event. Accordingly, we present a case of a right atrial thrombus not amenable to medical therapy that was removed only after concomitant utilization of an AngioVac Aspiration System (Vortex Medical, Norwell, MA) and percutaneous snare catheterization.
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