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Published on: April 14, 2011
Plastic bronchitis associated with influenza virus infection in children: a report on 14 cases
1Department of Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, China.
Background:
Plastic bronchitis (PB) is a rare disease characterized by formation of bronchial casts. It is usually associated with congenital heart disease, sickle cell disease, lymphoma, and lung diseases such as asthma and pneumonia.
Objectives:
To report 14 cases of PB with influenza A or influenza B infection.
Methods:
We analyzed the clinical manifestations, bronchoscopic and histologic findings, clinical courses, and outcomes.
Results:
These cases indicate that PB is a life-threatening complication of severe influenza. Plastic bronchitis should be considered in the diagnosis of children with acute respiratory distress such as lung atelectasis accompanied by influenza.
Conclusions:
Diagnosis should be made by bronchial endoscopy and histopathology, and bronchial casts removed as early as possible.
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