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Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
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[Corneal transplantations in the Czech Republic in 2012]
Summary
In 2012, bullous keratopathy was the leading reason for corneal transplants in the Czech Republic. Lamellar keratoplasty, particularly posterior lamellar keratoplasty, is increasingly common in corneal transplantation procedures.
Area of Science:
- Ophthalmology
- Transplantation Surgery
- Public Health
Background:
- Corneal transplantation is a vital surgical procedure for restoring vision.
- Understanding current trends in corneal transplantation is crucial for optimizing patient care and resource allocation.
Purpose of the Study:
- To analyze the frequency and types of corneal transplantations performed in the Czech Republic in 2012.
- To identify the primary indications for corneal transplantation in the Czech Republic during 2012.
Main Methods:
- A nationwide survey was conducted among clinics performing corneal transplantations.
- Data on transplant numbers, types, and indications were collected via questionnaires.
- Information was cross-referenced with the annual report of corneal tissue banks for 2012.
Main Results:
- A total of 465 corneal transplantations were analyzed, representing 92.8% of issued corneas.
- Bullous keratopathy (40%) was the most frequent indication, followed by keratoconus (19.1%) and endothelial dystrophy (16.1%).
- Penetrating keratoplasty (50.75%) was the most common procedure, with posterior lamellar keratoplasty (44.95%) and anterior lamellar keratoplasty (4.3%) also significant.
Conclusions:
- The study indicates a growing trend towards lamellar keratoplasty, especially posterior lamellar keratoplasty.
- Endothelial corneal dystrophies, including bullous keratopathy, are major drivers for corneal transplantation.
- Keratoconus accounts for approximately 20% of indications for corneal transplantation.
