Primary intraosseous meningioma mimicking osteosarcoma: case report
Related Experiment Video
Updated: Apr 18, 2026
Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Kıyasettin Asil1, Yakup Ersel Aksoy, Can Yaldiz
1Sakarya Training and Research Hospital, Department of Radiology, Sakarya, Turkey.
Abstract:
With an incidence rate of 15-20%, meningiomas are one of the most common brain tumors among benign intracranial tumors. They are distributed as follows in intracranial localizations: parasagittal and falx (25%), convexity (18%), sphenoid wing (18%), parasellar (12%), posterior fossa (10%), intraventricular (2%), intraorbital (1%), and extracranial (1%). The most common extradural localizations are the paranasal sinuses, nasal cavity, skin, neck, glands, and intraosseous space. Intradiploic meningiomas are generally localized in the frontoparietal and orbital regions. Due to their low incidence and lack of adequate preoperative diagnostic testing, intradiploic meningiomas are generally mistaken for primary calvarial bone tumors and en plaque meningiomas. Our case was discussed here with literature findings since primary intradiploic meningioma is uncommon and poses diagnostic challenges.
Insights
Intradiploic meningiomas, a rare type of benign brain tumor, often present diagnostic challenges. This case highlights the difficulties in diagnosing these uncommon tumors, which are frequently misidentified as primary bone tumors.
Area of Science:
- Neurosurgery
- Oncology
- Radiology
Background:
- Meningiomas are common benign intracranial tumors with a 15-20% incidence rate.
- They exhibit diverse intracranial and extradural localizations, including rare intraosseous sites.
Observation:
- Intradiploic meningiomas, typically in frontoparietal and orbital regions, are infrequently diagnosed preoperatively.
- These tumors are often misdiagnosed as primary calvarial bone tumors or en plaque meningiomas due to low incidence and diagnostic limitations.
Findings:
- This case report discusses a primary intradiploic meningioma, emphasizing its rarity.
- Literature findings are reviewed to address the diagnostic challenges associated with this specific meningioma subtype.
Implications:
- Improved preoperative diagnostic strategies are needed for intradiploic meningiomas.
- Enhanced awareness among clinicians can lead to earlier and more accurate diagnosis of these rare tumors.
