Collimator Width Optimization in X-Ray Luminescent Computed Tomography (XLCT) with Selective Excitation Scheme

X-ray luminescent computed tomography (XLCT) is a promising new functional imaging modality based on computed tomography (CT). This imaging technique uses X-ray excitable nanophosphors to illuminate objects of interest in the visible spectrum. Though there are several validations of the underlying technology, none of them have addressed the issues of performance optimality for a given design of the imaging system. This study addresses the issue of obtaining best image quality through optimizing collimator width to balance the signal to noise ratio (SNR) and resolution. The results can be generalized as to any XLCT system employing a selective excitation scheme.