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Pediatric neurocysticercosis: three cases presented in the Netherlands with divergent clinical presentations
Laura A van de Pol1, T E M van Doeveren1, M van der Kuip2
1Department of Child Neurology, VU University Medical Center, Amsterdam, The Netherlands.
Insights
Neurocysticercosis, a central nervous system infection caused by pork tapeworm larvae, is increasingly seen in Western Europe. Prompt recognition of brain lesions is key to effective management and avoiding unnecessary interventions.
Area of Science:
- Neurology
- Infectious Diseases
- Parasitology
Background:
- Neurocysticercosis is a parasitic infection of the central nervous system caused by Taenia solium larvae.
- Increasing immigration from endemic regions leads to a rise in neurocysticercosis cases in Western Europe.
Background:
Neurocysticercosis is a helminthic disease that affects the central nervous system by the larvae of the Taenia solium, the pork tapeworm. Because of the growing number of immigrants from endemic areas, its incidence is increasing in Western Europe.
Cases:
We describe three children, aged between 2 and 13 years, two of whom have a definite and one a probable diagnosis of neurocysticercosis based on the "Del Brutto criteria." They presented with different symptoms and signs: symptomatic epilepsy, asymmetric cerebral palsy, and headache. Serological evaluation was negative in two of the three cases. All cases showed comparable abnormalities on magnetic resonance imaging of the brain: solitary or multiple, cystic lesions, with surrounding edema. In one of them, the "scolex" (part of the larvae) could be visualized. One case was treated with albendazole, the other two cases did not receive medication.
Conclusion:
A prompt diagnosis of neurocysticercosis by recognition of its typical brain lesions is important to prevent unnecessary diagnostic tests and treatment.
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