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Updated: Apr 17, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
[Time from motor symptoms onset to diagnosis of Parkinson's disease in Mexico]
Amin Cervantes Arriaga1, Mayela Rodríguez Violante1, Azyadeh Camacho Ordóñez1
1Instituto Nacional de Neurología y Neurocirugía, México, D.F.
Introduction:
Parkinson's disease is characterized by a wide spectrum of motor and non-motor symptoms with an insidious onset. Identification of these symptoms by the patient as well as by the physician is determinant in order to achieve an early diagnosis.
Objective:
To determine the time from motor symptoms onset to the diagnosis of Parkinson's disease and analyze the clinical and demographic factors related to it.
Material And Methods:
A cross-sectional study was carried out including subjects with Parkinson's disease seen during the 2011-2012 period and belonging to the Mexican National Parkinson's Registry. Time from symptom onset to the diagnosis was collected; its relation with demographic and clinical characteristics was assessed.
Results:
A total of 1,062 subjects were included. Delay in diagnosis was 29.5 months. Predictive factors for a longer diagnostic delay were symptoms onset before 40 years of age (B: -0.350; p < 0.001) and a positive family history of Parkinson's disease (B: 0.224; p < 0.001).
Conclusions:
The diagnosis of Parkinson´s disease in Mexico is two and a half times greater than what has been reported for other countries.
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